Sucralose -- Absorption and Accumulation
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Sucralose (Splenda) Toxicity Information Center
According to the U.S. Food and Drug Administration, 11 to 27
percent of ingested sucralose is absorbed by the human body (FDA 1998).
Research published by the manufacturer of sucralose (Roberts 2000)
shows that when 8 healthy male adults where given sucralose
(in 1 mg/kg amounts), between 10.4% and 30.6% of the sucralose was
absorbed. In addition, 1.6% to 12.2% of the sucralose accumulates
in the body. See Table 2 in
Roberts (2000). No information is given as to whether it accumulates
as sucralose or other chemicals
Web page revision in progress.... To be continued shortly....
FDA 1998. Food Additives Permitted for Direct Addition to Food for Human
Consumption; Sucralose," 21 CFR Part 172, Docket No. 87F-0086, 1998.
Federal Register: April 3, 1998 (Volume 63, Number 64, Page 16417-16433).
Roberts, A., A.G. Renwick, J. Sims, D.J. Snodin, 2000. "Sucralose Metabolism
and Pharmacokinetics in Man," Food and Chemical Toxicology, Volume 38,
Supplement 2, pages S31-S41, 2000.